Publications

Francesca-Zhoufan Li, Lukas A. Radtke, Kadina E. Johnston, Cheng-Hao Liu, Yisong Yue, Frances H. Arnold (2025). Substrate-Aware Zero-Shot Predictors for Non-Native Enzyme Activities. GEM Bio Workshop at ICLR 2025.

Yueming Long, Ariane Mora, Francesca-Zhoufan Li, Emre Gürsoy, Kadina E. Johnston, Frances H. Arnold (2024). LevSeq: Rapid Generation of Sequence-Function Data for Directed Evolution and Machine Learning. ACS Synthetic Biology.

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Francesca-Zhoufan Li, Jason Yang, Kadina E. Johnston, Emre Gürsoy, Yisong Yue, Frances H. Arnold (2024). Evaluation of Machine Learning-Assisted Directed Evolution Across Diverse Combinatorial Landscapes. bioRxiv.

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Francesca-Zhoufan Li, Ava P. Amini, Yisong Yue, Kevin K. Yang, Alex X. Lu (2024). Feature Reuse and Scaling: Understanding Transfer Learning with Protein Language Models. Proceedings of the 41st International Conference on Machine Learning, PMLR 235:27351-27375.

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Jason Yang, Francesca-Zhoufan Li, Frances H Arnold (2024). Opportunities and Challenges for Machine Learning-Assisted Enzyme Engineering. ACS Central Science.